Host-pathogen interactions in Drosophila
نویسندگان
چکیده
منابع مشابه
Deconstructing host-pathogen interactions in Drosophila
Many of the cellular mechanisms underlying host responses to pathogens have been well conserved during evolution. As a result, Drosophila can be used to deconstruct many of the key events in host-pathogen interactions by using a wealth of well-developed molecular and genetic tools. In this review, we aim to emphasize the great leverage provided by the suite of genomic and classical genetic appr...
متن کاملMining Host-Pathogen Interactions
containing HPI information and another abstract that does not. Using a training set of pre-annotated abstracts, the system can then learn how to efficiently discriminate between these two abstract types. Moreover, the same characteristic features can be calculated for the individual sentences in the abstract. Thus, we can use the same supervised-learning approach to solve Tasks 1 and 2. Finally...
متن کاملArrestins in host-pathogen interactions.
In the context of host-pathogen interaction, host cell receptors and signaling pathways are essential for both invading pathogens, which exploit them for their own profit, and the defending organism, which activates early mechanism of defense, known as innate immunity, to block the aggression. Because of their central role as scaffolding proteins downstream of activated receptors, β-arrestins a...
متن کاملHost-Pathogen Interactions in Tuberculosis
My presentation will focus on host-cell pathogen interactions in tuberculosis. However, I would first like offer a brief introduction to the tuberculosis disease. I believe it is important to remember that merely an estimated 5-10% of individuals exposed or infected with the Mycobacterium tuberculosis bacteria actually develop tuberculosis. In other words, the human population, as a whole, is e...
متن کاملPAK in pathogen-host interactions
Eukaryotic, prokaryotic and viral pathogens are known to interfere with signaling pathways of their host to promote their own survival and proliferation. Here, we present selected examples of modulation of PAK activity in human cells by both intracellular and extracellular pathogens, focusing on one eukaryotic pathogen, the human malaria parasite Plasmodium falciparum, two Gram-negative bacteri...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Disease Models & Mechanisms
سال: 2008
ISSN: 1754-8411,1754-8403
DOI: 10.1242/dmm.000877